Linear 1 3-diarylpropanoids
Medchemexpress LLC Pinostrobin chalcone | 18956-15-5 | 5 MG
Pinostrobin chalcone is a potent natural cytotoxic compound with anti-inflammatory properties. It has shown cytotoxic effects against MDA-MB-231 and HT-29 colon cancer cell lines and exhibits anti-inflammatory activity by inhibiting LPS-induced IL-1beta mRNA expression in J774.A1 and RAW264.7 cells. This product is for research use only.
- Potent natural cytotoxic compound
- Exhibits cytotoxic effects against MDA-MB-231 and HT-29 colon cancer cell lines
- Shows anti-inflammatory activity against mouse J774.A1 and RAW264.7 cells
- Inhibits LPS-induced IL-1beta mRNA expression
- Tested for antiproliferative activity against MCF-7 human breast cancer cells
Medchemexpress LLC (E)-Naringenin chalcone | 25515-46-2 | 1 MG
(E)-Naringenin chalcone is an orally active anti-allergic agent that also possesses antioxidant and anti-inflammatory activities. It can improve adipocyte functions and inhibits histamine release from rat peritoneal mast cells. This product is for research use only.
- Orally active anti-allergic agent
- Possesses antioxidant activities
- Exhibits anti-inflammatory activities
- Improves adipocyte functions
- Inhibits histamine release from rat peritoneal mast cells
Medchemexpress LLC Trans-aconitic acid | 4023-65-8 | MFCD00002721 | ≥98.0% | 174.11 | C6H6O6 | 10 MG
trans-aconitic acid (CAS 4023-65-8) is an analytical reference standard for metabolite analysis and method validation. It is supplied as a white to off-white solid with molecular formula C6H6O6 and molecular weight 174.11, intended for research and analytical applications.
- Purity (NMR) ≥98.0%.
- White to off-white solid suitable for analytical use.
- Stable as a powder: -20°C (3 years), 4°C (2 years).
- Stable in solvent under cold storage: -80°C (6 months), -20°C (1 month).
- Suitable for reference, calibration, and method development.
Medchemexpress LLC 4'-Methoxychalcone | 959-23-9 | 99.8% | 50 G
4'-Methoxychalcone is a compound that regulates adipocyte differentiation through PPARγ activation. It modulates the expression and secretion of various adipokines in adipose tissue, which are involved in insulin sensitivity.
- Regulates adipocyte differentiation via PPARγ activation.
- Modulates adipokine expression and secretion.
- Increases mRNA expression of adipogenic genes during differentiation.
- Reduces upregulated mRNA expression of inflammatory markers in preadipocyte cells.
- Exhibits antiproliferative and cytotoxic activity against various human and mouse cell lines.
eMolecules 299165-27-8 | Amino(4-tert-butylphenyl)acetic acid | MFCD02662470 | 1g
Ambeed | 3-Iodopicolinic acid | 250mg | 490537107 | A220091 | 73841-32-4 | MFCD01928487 | 249.007 | C6H4INO2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC HY-107818 100mg Medchemexpress, 4-Hydroxychalcone CAS:20426-12-4 Purity:>98%
Medchemexpress, HY-107818 100mg 4-Hydroxychalcone CAS:20426-12-4 4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Naringenin 480-41-1 10mM (in 1mL DMSO)
Naringenin (CAS 480-41-1) is a small-molecule inhibitor designed to modulate inflammatory and antiviral pathways thereby regulating cellular inflammatory responses and viral replication Naringenin exerts its biological activity primarily through inhibition of the NF- B pathway resulting in reduced inflammatory cytokine production Additionally it demonstrates antioxidative properties by scavenging reactive oxygen species (ROS) In in vitro studies naringenin exhibits inhibition of dengue virus replication with reported IC50 values ranging from approximately 52 64 M to 143 M depending on experimental conditions and viral strains Based on these pharmacological properties naringenin holds research potential in inflammation oxidative stress-related cellular models and dengue virus infection studies
Apexbio Technology LLC Phloretin 60-82-2 10mM (in 1mL DMSO)
Phloretin (CAS 60-82-2) is a naturally occurring dihydrochalcone phenolic compound derived primarily from apple leaves and Manchurian apricot It functions as an inhibitor of sodium-glucose linked transporters (SGLT1 and SGLT2) proteins involved in glucose uptake and reabsorption in intestinal and renal tissues Phloretin inhibits glucose uptake via these transporters exhibiting an IC50 of approximately 49 12 M In cell-based studies it enhances lipolysis increases AMP-activated protein kinase (AMPK) phosphorylation and suppresses adipogenic transcription factors and MAPK signaling Animal research demonstrates that oral administration of Phloretin reduces blood glucose and improves lipid profiles in diabetic mouse models highlighting its utility in metabolic research
Medchemexpress LLC Chalcone 4 hydrate 1mg | 1202866-96-3 | ≈288.73 g/mol (anhydrous basis); varies with hydration (xH2O) | C16H13ClO3·xH2O | 1 MG
Chalcone 4 hydrate (CAS 1202866-96-3) is an anti-parasite small-molecule research reagent reported to inhibit the growth of Babesia and Theileria. The compound is supplied as a hydrated solid and is intended for in vitro parasitology and chemical biology studies; handle and store under recommended conditions.
- Hydrated solid form (xH2O)
- Purity 98.0%
- Molecular formula C16H13ClO3·xH2O
- Typical molecular weight ~288.73 g/mol (anhydrous basis)
- Offered in low-quantity research sizes (e.g., 1 mg)
- Store at 4°C; in solution, store -80°C up to 6 months or -20°C up to 1 month under nitrogen
Medchemexpress LLC Dihydrochalcone 25g | 1083-30-3 | 210.27 g/mol | C15H14O | 25 G
Dihydrochalcone (CAS 1083-30-3) is a small-molecule research reagent supplied as a high-purity solid for in vitro and analytical applications.
- High purity ≥98%.
- Molecular formula C15H14O.
- Molecular weight 210.27 g/mol.
- Suitable for in vitro biochemical assays and as an analytical reference.
- Available in a 25 G pack for laboratory use.
Medchemexpress LLC Xanthohumol | 6754-58-1 | 354.40 | 50 MG
Xanthohumol is a prominent flavonoid isolated from hops. It acts as an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2. It exhibits anti-cancer and anti-angiogenic activities. Additionally, Xanthohumol possesses antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Inhibits diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2.
- Possesses anti-cancer activities.
- Exhibits anti-angiogenic activities.
- Shows antiviral activity against BVDV, rhinovirus, HSV-1, HSV-2, and CMV.
Medchemexpress LLC Naringin Dihydrochalcone | 18916-17-1 | 99.2% | 582.55 | 5 G
Naringin Dihydrochalcone is an artificial sweetener synthesized from naringin, a flavanone glycoside naturally found in citrus fruits like tomatoes and grapefruits. It demonstrates various biological properties, including antioxidant, anti-inflammatory, and antiapoptotic effects, and is known to suppress the NF-κB signaling pathway.
- Artificial sweetener.
- Derived from naringin, a flavanone glycoside.
- Exhibits antioxidant, anti-inflammatory, and antiapoptotic activities.
- Suppresses NF-κB signaling pathway.
- Inhibits high glucose-induced proliferation and oxidative stress in HBZY-1 cells.
- Induces autophagic cell death in AGS cancer cells.
- Protects PC12 cells from neurotoxicity and enhances antioxidant defense.
- Alleviates renal injury, collagen deposition, and fibrosis in diabetic rats.
- Improves learning, memory, and insulin signaling in high-fat diet-induced obese mice.
